To succeed in this topic, you need to:
Be familiar with the structure of the atom; isotopes and the isotopic composition of elements.
• Be familiar with organic nomenclature and displaying organic compounds.
• Be familiar with the purpose of analytical techniques in determining the chemical composition and structure of substances.

After working through this Chemistry Factsheet, you will:
Be aware of the general principles in mass spectrometry, including field mass analysers and time-of-flight analysers, and the separation of ions due to their mass-to-charge ratios (m/z).
• Be aware of the methods for using mass spectra to measure isotopic abundance, and for determining the structures of organic compounds using fragmentation patterns.
• Be aware of using key peaks, such as the M+1 peak, M+2 peak and the nitrogen rule, when interpreting mass spectra to help determine the structures of organic compounds.

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Publication Date

April 2019


ISSN: 1351-5136

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293 Mass Spectrometry V2

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